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The best Innovation ETFs

How to invest in innovative technologies using ETFs

0.18% p.a. - 0.89% p.a.
annual total expense ratio (TER) of innovation ETFs
24 Indices
on innovative technologies, which are tracked by ETFs
25 ETFs
on innovative technologies
 
The best indices for innovation ETFs

How do I invest in innovative technologies?

Gaining new insights through research and using these insights to develop and implement new technologies is part of the business model of many companies.

Many of these efforts, with particular economic impact and dissemination, are expected to be in the health sector. The same applies to digital technologies, whose effects will probably not result in evolution but in a complete transformation of value chains and sales processes. Index providers evaluate companies according to their ambitions for innovation and construct specific indices based on this information.

In this investment guide, you will find all ETFs that allow you to invest in innovative technologies. Currently, there are 25 ETFs available.
 

iSTOXX® FactSet Breakthrough Healthcare performance

1 month: 5.00%
1 year: 4.30%
3 years: 7.77%
5 years: -2.39%
 

Innovation ETFs in comparison

The most important factors at a glance

When choosing an innovation ETF one should consider several other factors in addition to the methodology of the underlying index and performance of an ETF. For better comparison, you will find a list of all innovation ETFs with details on size, cost, age, income, domicile and replication method ranked by fund size.

Compare all innovation ETFs in detail
Compare all innovation ETFs in a chart

ETF name
ISIN		   Fund size
in m EUR		 TER
in %		 Use of profits Fund domicile Replication method
iShares Healthcare Innovation UCITS ETFIE00BYZK4776 921 0.40% p.a. Accumulating Ireland Optimized sampling
UBS Solactive China Technology UCITS ETF USD accLU2265794276 549 0.47% p.a. Accumulating Luxembourg Full replication
ARK Innovation UCITS ETF USD AccumulatingIE000GA3D489 305 0.75% p.a. Accumulating Ireland Full replication
Amundi MSCI Disruptive Technology UCITS ETF AccLU2023678282 153 0.45% p.a. Accumulating Luxembourg Full replication
L&G Healthcare Technology & Innovation UCITS ETF USD AccIE00BK5BC677 152 0.49% p.a. Accumulating Ireland Full replication
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF AccIE00BM8QS095 135 0.49% p.a. Accumulating Ireland Full replication
UBS Solactive China Technology UCITS ETF hEUR accLU2265794946 134 0.50% p.a. Accumulating Luxembourg Full replication
Amundi MSCI China Tech UCITS ETF EUR AccLU1681043912 125 0.55% p.a. Accumulating Luxembourg Full replication
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETFIE00BDDRF700 98 0.59% p.a. Accumulating Ireland Full replication
ARK Genomic Revolution UCITS ETF USD AccumulatingIE000O5M6XO1 41 0.75% p.a. Accumulating Ireland Full replication
Invesco ChiNext 50 UCITS ETF AccIE000AWRDWI7 35 0.49% p.a. Accumulating Ireland Full replication
Amundi MSCI China Tech UCITS ETF USD AccLU1681044050 35 0.55% p.a. Accumulating Luxembourg Full replication
UBS MSCI USA Tech 125 Universal UCITS ETF USD accIE0003B4BV34 34 0.18% p.a. Accumulating Ireland Full replication
WisdomTree Megatrends UCITS ETF USDIE0000902GT6 30 0.50% p.a. Accumulating Ireland Full replication
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C 1CLU2376679564 26 0.44% p.a. Accumulating Luxembourg Full replication
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1CLU2859297330 23 0.45% p.a. Accumulating Luxembourg Full replication
L&G Pharma Breakthrough UCITS ETFIE00BF0H7608 17 0.49% p.a. Accumulating Ireland Full replication
Harbor Health Care UCITS ETF AccumulatingIE00BJQTJ848 14 0.89% p.a. Accumulating Ireland Full replication
VanEck Genomics and Healthcare Innovators UCITS ETF AIE000B9PQW54 13 0.35% p.a. Accumulating Ireland Full replication
Xtrackers World Green Tech Innovators UCITS ETF 1CLU2859392081 12 0.35% p.a. Accumulating Luxembourg Full replication
Xtrackers MSCI Innovation UCITS ETF 1C 1CIE0006FFX5U1 7 0.30% p.a. Accumulating Ireland Full replication
First Trust Indxx NextG UCITS ETF AccIE00BWTNM743 7 0.70% p.a. Accumulating Ireland Full replication
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C 1CIE000KD0BZ68 7 0.30% p.a. Accumulating Ireland Full replication
KraneShares ICBCUBS SSE STAR Market 50 Index UCITS ETF IE00BKPJY434 6 0.82% p.a. Accumulating Ireland Full replication
First Trust Alerian Disruptive Technology Real Estate UCITS ETF AccIE000RN036E0 0 0.60% p.a. Accumulating Ireland Full replication

Source: justETF.com; As of 07.12.25

 

Find the best Innovation ETF

Return comparison of all innovation ETFs

The table shows the returns of all innovation ETFs in comparison. All return figures are including dividends as of month end. Besides the return the reference date on which you conduct the comparison is important. In order to find the best ETFs, you can also perform a chart comparison.

ETF   1 month
in %		 3 months
in %		 6 months
in %		 1 year
in %		 3 years
in %
UBS Solactive China Technology UCITS ETF hEUR acc -7.34% -2.71% 15.59% 51.89% 45.73%
UBS Solactive China Technology UCITS ETF USD acc -7.71% -1.20% 14.33% 38.95% 35.40%
Invesco ChiNext 50 UCITS ETF Acc -7.17% 7.07% 66.60% 36.33% -
ARK Innovation UCITS ETF USD Accumulating -6.24% 8.26% 41.10% 26.71% -
Amundi MSCI China Tech UCITS ETF USD Acc -8.77% 1.47% 29.08% 23.73% 14.80%
Amundi MSCI China Tech UCITS ETF EUR Acc -8.98% 1.53% 28.80% 23.42% 13.53%
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF Acc -7.50% 3.61% 15.71% 22.30% 20.78%
KraneShares ICBCUBS SSE STAR Market 50 Index UCITS ETF -8.51% -1.20% 32.58% 21.33% 4.25%
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C 1C -7.38% 2.89% 19.97% 20.58% 18.19%
L&G Pharma Breakthrough UCITS ETF 5.63% 17.42% 27.66% 18.34% 7.33%
First Trust Indxx NextG UCITS ETF Acc -3.01% 8.19% 15.72% 15.37% 56.17%
UBS MSCI USA Tech 125 Universal UCITS ETF USD acc -2.40% 9.47% 20.83% 12.12% -
Amundi MSCI Disruptive Technology UCITS ETF Acc -3.34% 9.10% 17.66% 9.91% 48.40%
L&G Healthcare Technology & Innovation UCITS ETF USD Acc 8.63% 19.78% 30.51% 9.64% 9.46%
ARK Genomic Revolution UCITS ETF USD Accumulating 4.58% 27.41% 45.51% 9.61% -
WisdomTree Megatrends UCITS ETF USD -5.28% 10.73% 21.48% 7.77% -
Xtrackers World Green Tech Innovators UCITS ETF 1C -0.19% 6.74% 14.40% 7.14% -
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETF -7.31% 3.64% 17.88% 6.49% 68.72%
Harbor Health Care UCITS ETF Accumulating 6.92% 16.53% 27.59% 6.30% 0.97%
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C 1C 7.59% 18.34% 31.76% 6.22% 0.68%
iShares Healthcare Innovation UCITS ETF 7.31% 15.43% 21.07% 5.31% 7.89%
VanEck Genomics and Healthcare Innovators UCITS ETF A 5.44% 13.14% 19.66% 4.95% -4.55%
Xtrackers MSCI Innovation UCITS ETF 1C 1C -0.90% 6.57% 11.87% 3.62% 55.50%
First Trust Alerian Disruptive Technology Real Estate UCITS ETF Acc -0.17% 1.62% -0.06% -10.12% -7.38%
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1C 1.75% 10.83% 22.18% - -
ETF   2025
in %		 2024
in %		 2023
in %		 2022
in %		 2021
in %
UBS Solactive China Technology UCITS ETF hEUR acc 43.88% 9.30% -12.24% -34.40% -
Invesco ChiNext 50 UCITS ETF Acc 42.88% - - - -
UBS Solactive China Technology UCITS ETF USD acc 29.49% 18.01% -13.60% -27.68% -
ARK Innovation UCITS ETF USD Accumulating 26.94% - - - -
KraneShares ICBCUBS SSE STAR Market 50 Index UCITS ETF 24.36% 12.30% -21.03% -34.49% -
L&G Pharma Breakthrough UCITS ETF 24.35% 1.37% -13.42% -1.53% 4.12%
Amundi MSCI China Tech UCITS ETF USD Acc 20.91% 8.38% -14.25% -3.27% 4.50%
Amundi MSCI China Tech UCITS ETF EUR Acc 20.78% 8.70% -14.17% -2.93% 3.78%
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C 1C 18.68% 22.19% -18.13% - -
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF Acc 18.39% 27.98% -21.40% -26.43% -
ARK Genomic Revolution UCITS ETF USD Accumulating 16.47% - - - -
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1C 16.46% - - - -
WisdomTree Megatrends UCITS ETF USD 14.56% 9.96% - - -
Harbor Health Care UCITS ETF Accumulating 13.08% -3.47% -1.92% -25.63% 1.00%
First Trust Indxx NextG UCITS ETF Acc 12.58% 19.82% 23.29% -19.74% 26.16%
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C 1C 10.83% 3.95% -7.06% - -
Amundi MSCI Disruptive Technology UCITS ETF Acc 10.44% 20.71% 19.39% -30.75% 10.36%
VanEck Genomics and Healthcare Innovators UCITS ETF A 10.11% 0.89% -8.09% - -
UBS MSCI USA Tech 125 Universal UCITS ETF USD acc 8.63% - - - -
iShares Healthcare Innovation UCITS ETF 8.48% 7.98% -1.46% -18.99% 1.80%
Xtrackers World Green Tech Innovators UCITS ETF 1C 8.03% - - - -
Xtrackers MSCI Innovation UCITS ETF 1C 1C 3.22% 29.60% 27.60% - -
First Trust Alerian Disruptive Technology Real Estate UCITS ETF Acc -2.98% -4.18% 9.24% - -
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETF -3.14% 22.50% 40.67% -41.42% 17.63%
L&G Healthcare Technology & Innovation UCITS ETF USD Acc -15.40% 9.53% -6.26% -29.18% 8.52%

Source: justETF.com; As of 30.11.25; Calculations in EUR including dividends