Ionis Pharmaceuticals
ISIN US4622221004
|WKN A2ACMZ
Overview
Description
Ionis Pharmaceuticals, Inc. engages in the development and commercialization of human therapeutic drugs using antisense technology. It operates through the Ionis Core segment. The Ionis Core segment exploits a novel drug discovery platform to generate a pipeline of drugs. The company was founded by Stanley T. Crooke, David J. Ecker, Christopher K. Mirabelli, and Brett P. Monia on January 10, 1989 and is headquartered in Carlsbad, CA.
Healthcare Biopharmaceuticals Other Biopharmaceuticals United States
Chart
Financials
Key metrics
| Market capitalisation, EUR | 5,414.36 m |
| EPS, EUR | -2.25 |
| P/B ratio | 8.48 |
| P/E ratio | - |
| Dividend yield | 0.00% |
Income statement (2023)
| Revenue, EUR | 728.56 m |
| Net income, EUR | -338.81 m |
| Profit margin | -46.50% |
What ETF is Ionis Pharmaceuticals in?
There are 32 ETFs which contain Ionis Pharmaceuticals. All of these ETFs are listed in the table below. The ETF with the largest weighting of Ionis Pharmaceuticals is the ARK Genomic Revolution UCITS ETF USD Accumulating.
| ETF | Weight | Investment focus | Holdings | TER | Fund size (in m EUR) | Return 1Y | WKN | ISIN |
|---|---|---|---|---|---|---|---|---|
| JPMorgan BetaBuilders US Small Cap Equity UCITS ETF USD (acc) | 0.11% | Equity United States Small Cap | 1,375 | 0.14% | 51 | +23.73% | A3DQ08 | IE000JNKVS10 |
| UBS ETF (IE) MSCI USA Select Factor Mix UCITS ETF (hedged to EUR) A-acc | 0.02% | Equity United States Multi-Factor Strategy | 1,953 | 0.28% | 7 | +16.81% | A2DWAC | IE00BDGV0746 |
| VanEck Morningstar US SMID Moat UCITS ETF A | 0.57% | Equity United States Small Cap Moat | 105 | 0.49% | 13 | - | A3ELCX | IE000SBU19F7 |
| WisdomTree BioRevolution UCITS ETF USD Acc | 1.16% | Equity World Health Care Social/Environmental Biotech | 89 | 0.45% | 3 | -5.98% | A3CY21 | IE000O8KMPM1 |
| iShares Healthcare Innovation UCITS ETF | 0.71% | Equity World Health Care Social/Environmental Innovation | 196 | 0.40% | 972 | +11.91% | A2ANH2 | IE00BYZK4776 |
| JPMorgan BetaBuilders US Small Cap Equity UCITS ETF USD (dist) | 0.11% | Equity United States Small Cap | 1,375 | 0.14% | 164 | +24.21% | A3DQ09 | IE0001O84583 |
| UBS ETF (IE) MSCI USA Select Factor Mix UCITS ETF (USD) A-dis | 0.02% | Equity United States Multi-Factor Strategy | 1,953 | 0.25% | 32 | +27.51% | A2DND0 | IE00BDGV0308 |
| L&G Global Thematic ESG Exclusions UCITS ETF USD Accumulating | 0.44% | Equity World Social/Environmental Innovation | 368 | 0.60% | 4 | +12.44% | A3DHPA | IE000VTOHNZ0 |
| iShares MSCI World Small Cap UCITS ETF | 0.06% | Equity World Small Cap | 3,321 | 0.35% | 4,796 | +16.96% | A2DWBY | IE00BF4RFH31 |
| Amundi Russell 1000 Growth UCITS ETF Acc | 0.02% | Equity United States Growth | 391 | 0.19% | 778 | +43.95% | ETF201 | IE0005E8B9S4 |
| Vanguard ESG North America All Cap UCITS ETF (USD) Accumulating | 0.01% | Equity North America Social/Environmental | 1,453 | 0.12% | 193 | +34.19% | A3DJRE | IE000O58J820 |
| iShares Russell 1000 Growth UCITS ETF USD (Acc) | 0.02% | Equity United States Growth | 375 | 0.18% | 175 | +44.87% | A3ECC1 | IE000NITTFF2 |
| WisdomTree Megatrends UCITS ETF USD | 0.06% | Equity World Social/Environmental Innovation | 650 | 0.50% | 15 | +16.21% | A3EYCN | IE0000902GT6 |
| VanEck Genomics and Healthcare Innovators UCITS ETF A | 1.44% | Equity World Health Care Social/Environmental Innovation | 53 | 0.35% | 5 | +6.51% | A3DSGJ | IE000B9PQW54 |
| Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C | 0.41% | Equity World Health Care Social/Environmental Innovation | 97 | 0.30% | 3 | +7.25% | DBX0R2 | IE000KD0BZ68 |
| SPDR MSCI ACWI IMI UCITS ETF USD Unhedged (Acc) | 0.03% | Equity World | 3,576 | 0.17% | 2,175 | +25.00% | A1JJTD | IE00B3YLTY66 |
| UBS ETF (IE) MSCI USA Select Factor Mix UCITS ETF (USD) A-acc | 0.02% | Equity United States Multi-Factor Strategy | 1,953 | 0.25% | 81 | +27.55% | A2JSD1 | IE00BDGV0415 |
| SPDR MSCI World Small Cap UCITS ETF | 0.06% | Equity World Small Cap | 3,545 | 0.45% | 890 | +16.42% | A1W56P | IE00BCBJG560 |
| ARK Genomic Revolution UCITS ETF USD Accumulating | 4.38% | Equity World Health Care Innovation | 37 | 0.75% | 4 | - | A408AY | IE000O5M6XO1 |
| iShares Ageing Population UCITS ETF | 0.47% | Equity World Health Care Social/Environmental Ageing Population | 343 | 0.40% | 355 | +18.08% | A2ANH1 | IE00BYZK4669 |
| Vanguard ESG Global All Cap UCITS ETF (USD) Distributing | 0.01% | Equity World Social/Environmental | 5,774 | 0.24% | 407 | +26.93% | A2QL8V | IE00BNG8L385 |
| SPDR MSCI ACWI IMI UCITS ETF USD Unhedged (Dist) | 0.03% | Equity World | 3,576 | 0.17% | 14 | - | A40F93 | IE000DD75KQ5 |
| UBS ETF (IE) MSCI USA Select Factor Mix UCITS ETF (hedged to CHF) A-acc | 0.02% | Equity United States Multi-Factor Strategy | 1,953 | 0.28% | 24 | +15.18% | A2DWAB | IE00BDGV0C91 |
| iShares MSCI USA Small Cap ESG Enhanced UCITS ETF (Acc) | 0.03% | Equity United States Small Cap | 1,602 | 0.43% | 2,211 | +20.31% | A0X8SB | IE00B3VWM098 |
| iShares Nasdaq US Biotechnology UCITS ETF USD (Dist) | 0.57% | Equity United States Health Care Biotech | 213 | 0.35% | 30 | +11.66% | A2JDYM | IE00BDZVHG35 |
| iShares Nasdaq US Biotechnology UCITS ETF | 0.57% | Equity United States Health Care Biotech | 213 | 0.35% | 436 | +11.01% | A2DWAW | IE00BYXG2H39 |
| SPDR MSCI USA Small Cap Value Weighted UCITS ETF | 0.01% | Equity United States Small Cap | 1,695 | 0.30% | 564 | +18.04% | A12HU5 | IE00BSPLC413 |
| iShares MSCI World Small Cap ESG Enhanced UCITS ETF USD (Acc) | 0.02% | Equity World Small Cap | 2,278 | 0.35% | 59 | +16.12% | A3C14G | IE000T9EOCL3 |
| Vanguard ESG North America All Cap UCITS ETF (USD) Distributing | 0.01% | Equity North America Social/Environmental | 1,453 | 0.12% | 29 | +34.18% | A3DJRF | IE000L2ZNB07 |
| Invesco Dow Jones Islamic Global Developed Markets UCITS ETF Acc | 0.01% | Equity World Islamic Investing | 1,592 | 0.40% | 836 | +28.59% | A3C6Z0 | IE000UOXRAM8 |
| Vanguard ESG Global All Cap UCITS ETF (USD) Accumulating | 0.01% | Equity World Social/Environmental | 5,774 | 0.24% | 450 | +26.57% | A2QL8U | IE00BNG8L278 |
| L&G Pharma Breakthrough UCITS ETF | 2.26% | Equity World Health Care Innovation | 37 | 0.49% | 17 | +3.43% | A2H9XR | IE00BF0H7608 |
Performance
Returns overview
| YTD | -28.63% |
| 1 month | +1.25% |
| 3 months | -11.63% |
| 6 months | -12.01% |
| 1 year | -25.95% |
| 3 years | +15.53% |
| 5 years | -40.08% |
| Since inception (MAX) | -39.68% |
| 2023 | +28.14% |
| 2022 | +36.82% |
| 2021 | -46.15% |
| 2020 | -7.84% |
Monthly returns in a heat map
Risk
Risk metrics in this section:
- Volatility, annualised, measured for 1, 3 and 5 year periods. The annualised volatility reflects the degree of price fluctuations during a one year period. The higher the volatility, the more significantly the price of the asset (stock, ETF, etc.) has changed in the past. Assets with higher volatility are generally considered more risky. We calculate the volatility based on the data for the past 1, 3 and 5 years so that you can see if price fluctuations for the ETF became stronger or weaker over time.
- Return per risk for 1, 3 and 5 year periods. This is the annualised (i.e. converted to a one year period) past return divided by the past annualised volatility. The metric puts the historical return of an asset in relation to its historical risk and gives you a retrospective indication of the degree of price fluctuation you had to bear with in order to obtain the return. We calculate this parameter for 1, 3 and 5 year periods to display its evolution over time.
- Maximum drawdown for a period. This shows the worst possible loss an investor could have suffered during the respective period, by first buying and subsequently selling the asset at the least favourable prices. For example, if there was the following sequence of daily ETF prices: 10€, 5€, 12€, 20€, an investor would have suffered the worst loss by buying for 10€ and subsequently selling for 5€. Therefore in this case the maximum drawdown would be (5€ - 10€)/10€ = -50%.
Risk overview
| Volatility 1 year | 35.52% |
| Volatility 3 years | 37.82% |
| Volatility 5 years | 39.60% |
| Return per risk 1 year | -0.73 |
| Return per risk 3 years | 0.13 |
| Return per risk 5 years | -0.25 |
| Maximum drawdown 1 year | -36.69% |
| Maximum drawdown 3 years | -36.69% |
| Maximum drawdown 5 years | -60.84% |
| Maximum drawdown since inception | -72.16% |
Rolling 1 year volatility
— Data provided by Trackinsight, etfinfo, Xignite Inc., gettex, FactSet and justETF GmbH. Quotes are either real-time (gettex) or 15 minutes delayed stock exchange quotes or NAVs (daily published by the fund provider). By default, ETF returns include dividend payments (if applicable). There is no warranty for completeness, accuracy and correctness for the displayed information.