The best Biotech ETFs

How to invest in biotech using ETFs

0.35% p.a. - 0.50% p.a.
annual total expense ratio (TER) of biotech ETFs
on biotech, which are tracked by ETFs
on biotech
 
The best indices for biotech ETFs

How do I invest in biotech stocks?

The main objective of biotech companies is to develop new or more efficient methods of diagnosis and ways of producing chemical compounds. For this purpose, knowledge from various fields of natural science is employed, mostly in combination with the latest digital technology. The outcomes are then used in medicine, agriculture or industry.

Biotech indices track companies that are active in these fields as well as firms that provide the relevant infrastructure.

In this investment guide, you will find all the ETFs that give you exposure to biotech stocks. Currently, there is 3 index available tracked by 5 ETFs.
 

Nasdaq Biotechnology performance

1 month: -2.84%
1 year: 11.63%
3 years: 0.89%
5 years: 23.58%
 

Biotech ETFs in comparison

The most important factors at a glance

When choosing a biotech ETF one should consider several other factors in addition to the methodology of the underlying index and performance of an ETF. For better comparison, you will find a list of all biotech ETFs with details on size, cost, age, income, domicile and replication method ranked by fund size.

Compare all biotech ETFs in detail
Compare all biotech ETFs in a chart

Provider
ISIN
  Fund size
in m EUR
TER
in %
Use of profits Fund domicile Replication method
iShares Nasdaq US Biotechnology UCITS ETFIE00BYXG2H39 439 0.35% p.a. Accumulating Ireland Optimized sampling
Invesco Nasdaq Biotech UCITS ETFIE00BQ70R696 282 0.40% p.a. Accumulating Ireland Unfunded swap
iShares Nasdaq US Biotechnology UCITS ETF USD (Dist)IE00BDZVHG35 31 0.35% p.a. Distributing Ireland Optimized sampling
Global X Genomics & Biotechnology UCITS ETFIE00BM8R0N95 9 0.50% p.a. Accumulating Ireland Full replication
WisdomTree BioRevolution UCITS ETF USD AccIE000O8KMPM1 3 0.45% p.a. Accumulating Ireland Full replication

Source: justETF.com; As of 25.12.24

 

Return comparison of all biotech ETFs

The table shows the returns of all biotech ETFs in comparison. All return figures are including dividends as of month end. Besides the return the reference date on which you conduct the comparison is important. In order to find the best ETFs, you can also perform a chart comparison.

ETF   1 month
in %
3 months
in %
6 months
in %
1 year
in %
3 years
in %
iShares Nasdaq US Biotechnology UCITS ETF USD (Dist) 0.79% -0.16% 8.61% 24.67% 5.59%
iShares Nasdaq US Biotechnology UCITS ETF 0.95% 0.00% 8.69% 24.61% 5.63%
Invesco Nasdaq Biotech UCITS ETF 0.91% -0.07% 8.58% 24.58% 5.66%
WisdomTree BioRevolution UCITS ETF USD Acc 4.26% -0.30% 4.46% 10.08% -
Global X Genomics & Biotechnology UCITS ETF 4.64% -0.28% 8.25% 7.60% -42.74%
ETF   2024
in %
2023
in %
2022
in %
2021
in %
2020
in %
iShares Nasdaq US Biotechnology UCITS ETF 11.73% 0.53% -5.02% 7.94% 15.18%
iShares Nasdaq US Biotechnology UCITS ETF USD (Dist) 10.48% 0.76% -5.13% 8.09% 15.15%
Invesco Nasdaq Biotech UCITS ETF 10.45% 0.54% -4.94% 7.96% 15.30%
WisdomTree BioRevolution UCITS ETF USD Acc -0.30% -6.11% -21.49% - -
Global X Genomics & Biotechnology UCITS ETF -4.24% -11.72% -32.85% - -

Source: justETF.com; As of 30.11.24; Calculations in EUR including dividends